The Museum holds a collection of 19th- and 20th-century American art, housed in a renovated 19th-century mill with a dramatic steel and glass addition overlooking the River. Known for its holdings of the Wyeth family of artists, the Museum shows the work of N.C., Andrew, and Jamie Wyeth.
The collection is a cross section of American art, with a focus on artistic practice in the Brandywine valley. 19th- and 20th-century landscapes, portraits, still life paintings, and notable holdings in American illustration add diversity and breadth to this unique collection.
A robust program of changing exhibitions places the Museum’s collection into the broader context of American art.
The N.C. Wyeth House and Studio and the Andrew Wyeth Studio are National Historic Landmarks, retaining much of their original character, with furnishings, library, art materials, and the artists' collections intact. Both are located near the Museum and scheduled tours depart from the Museum via shuttle.